hdac6 inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1983	CAY10603	HDAC6 Inhibitor,BML-281	HDAC
	CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.		HDAC
T10255	AES-135		HDAC
	AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.		HDAC
T3661	Citarinostat	ACY241,HDAC-IN-2	HDAC
	ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...		HDAC
T6481	Droxinostat	NS 41080	Apoptosis , HDAC
	Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.		Apoptosis , HDAC
T10777	CG347B		HDAC
	CG347B is a selective inhibitor of HDAC6.		HDAC
T69735	ITF3756		HDAC
	ITF3756 is a selective HDAC6 inhibitor.		HDAC
T7385	WT-161		Apoptosis , HDAC
	WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).		Apoptosis , HDAC
T2489	Ricolinostat	ACY-1215,Rocilinostat	Apoptosis , HDAC
	Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.		Apoptosis , HDAC
T1819	Nexturastat A		HDAC
	Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.		HDAC
T16129	MPI_5a		HDAC
	MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).		HDAC
T16936	SS-208		HDAC
	SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.		HDAC
T25175	BRD 9757	BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757	HDAC
	BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).		HDAC
T5332	TH34		HDAC
	TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.		HDAC
T6161	Tubastatin A Hydrochloride	TSA HCl,Tubastatin A HCl	Apoptosis , HDAC , Autophagy
	Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM). It has selectivity (>1000-fold) against all other isozymes except HDAC8 (>57-fold).		Apoptosis , HDAC , Autophagy
T2430	HPOB		Apoptosis , HDAC
	HPOB is an effective and specific HDAC6 inhibitor (IC50: 56 nM), >30-fold selectivity over other HDACs.		Apoptosis , HDAC
T60082	HDAC-IN-40		HDAC
	HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects		HDAC
T6421	BRD73954		HDAC
	BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.		HDAC
T6327	Tubacin		Virus Protease , HDAC
	Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.		Virus Protease , HDAC
T10244	ACY-1083		HDAC
	ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.		HDAC
T4370	Resminostat hydrochloride	4SC-201 hydrochloride,RAS2410 hydrochloride	HDAC
	Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM).		HDAC